RecruitingNot ApplicableNCT07244939

Cephea South America Feasibility Study


Sponsor

Abbott Medical Devices

Enrollment

20 participants

Start Date

Jun 17, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to evaluate the preliminary safety and effectiveness of the Cephea Mitral Valve System for the treatment of symptomatic patients with mitral valve disease (including mitral regurgitation, mitral stenosis and mixed mitral valve disease) in whom transcatheter therapy is deemed more appropriate than open heart surgery.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Mitral valve disease resulting in mitral regurgitation (MR ≥ Grade III) and/or severe mitral valve stenosis (mitral valve area ≤ 1.5cm²) per American Society of Echocardiography criteria
  • LVEF ≥ 30%
  • In the judgement of the Site Heart Team, transcatheter therapy is deemed more appropriate than open heart surgery

Exclusion Criteria2

  • Prior surgical or interventional treatment that interferes with the Cephea valve delivery or function
  • Need for emergent or urgent surgery

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Interventions

DEVICECephea Mitral Valve System

Cephea Mitral Valve System


Locations(3)

Instituto do Coracao (InCor) - HCFMUSP

São Paulo, Brazil

Instituto Nacional del Torax

Santiago, Chile

Hospital Clinico San Borja Arriarán

Santiago, Chile

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NCT07244939


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