Mitral Regurgitation Clinical Trials

8 recruiting

Frequently Asked Questions

Common questions about Mitral Regurgitation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 115 of 15 trials

Recruiting
Not Applicable

Efficacy and Safety of Catheter abLation in patiEnts With seVere mitrAl regurgiTation and pErsistent Atrial Fibrillation: a Randomized Controlled Trial

Atrial Fibrillation (AF)Catheter AblationAtrial Functional Mitral Regurgitation
Beijing Anzhen Hospital146 enrolled17 locationsNCT06883864
Recruiting

Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance

Heart Failure and Reduced Ejection FractionFunctional Mitral Regurgitation
Minneapolis Heart Institute Foundation125 enrolled6 locationsNCT07131631
Recruiting
Not Applicable

Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial

Mitral Regurgitation
Medtronic Cardiovascular400 enrolled37 locationsNCT05496998
Recruiting

In Search of Best Practices for Patients With Heart Failure and Secondary Mitral Regurgitation: An Evaluation of the Inova Heart Failure Treatment Algorithm

Heart FailureValvular Heart DiseaseMitral Regurgitation
Inova Health Care Services50 enrolled1 locationNCT06675448
Recruiting
Not Applicable

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

Heart FailureCardiovascular DiseasesHeart Diseases+3 more
Cardiac Dimensions, Inc.300 enrolled74 locationsNCT03142152
Recruiting

MItral Regurgitation Risk Assessment and CLinical modElling

Mitral InsufficiencyMitral Regurgitation (MR)
Sun Yat-sen University2,000 enrolled1 locationNCT06876883
Recruiting

The Multi-center Study of Comprehensive Atrial Fibrillation Regurgitation and Recurrent Events Evaluation

Atrial Fibrillation (AF)Tricuspid RegurgitationMitral Regurgitation
First Hospital of China Medical University2,000 enrolled1 locationNCT07085650
Recruiting
Not Applicable

The CardioClip Study

Heart Failure With Reduced Ejection FractionMitral Regurgitation
Columbia University60 enrolled1 locationNCT06241430
Recruiting

Atrial Functional Mitral Regurgitation and Tricuspid Regurgitation

Atrial FibrillationFunctional Mitral RegurgitationFunctional Tricuspid Regurgitation
Barts & The London NHS Trust141 enrolled1 locationNCT05920824
Recruiting
Not Applicable

Watchman for Patients With Atrial Fibrillation Undergoing Transcatheter Mitral Valve Repair (WATCH-TMVR)

Nonvalvular Atrial FibrillationSevere Degenerative Mitral Regurgitation
Mayo Clinic25 enrolled2 locationsNCT04494347
Recruiting

Study of Atrial Fibrillation Combined with Atrial Functional Mitral Regurgitation

Atrial Fibrillation (AF)Atrial Functional Mitral Regurgitation
Second Affiliated Hospital, School of Medicine, Zhejiang University500 enrolled1 locationNCT06630936
Recruiting
Not Applicable

Efficacy of MitraCLip Vs. PASCAL for the TrEAtment of MitraL REgurgiTation in an All-comer Population

Heart FailureValvular Heart DiseaseMitral Regurgitation
LMU Klinikum180 enrolled1 locationNCT06634121
Recruiting

MitraClip in Patients With Heart Failure

Mitral Regurgitation
The League of Clinical Research, Russia196 enrolled1 locationNCT06633159
Recruiting
Not Applicable

Mitral Regurgitation Treatment in Advanced Heart Failure

Heart FailureMitral Regurgitation
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia172 enrolled1 locationNCT05292716
Recruiting
Not Applicable

Evaluating Infrasonic Hemodynography

Cardiovascular DiseasesPulmonary HypertensionCoronary Artery Disease+3 more
Scripps Health25 enrolled1 locationNCT04636892