Evaluation Of Cardiovascular Health Outcomes Among Survivors 2
Evaluation Of Cardiovascular Health Outcomes Among Survivors 2 (ECHOS2)
St. Jude Children's Research Hospital
350 participants
Jun 1, 2026
INTERVENTIONAL
Conditions
Summary
Childhood cancer survivors who received certain treatments are at a higher risk of developing heart problems in the future. This study is looking at ways to educate childhood cancer survivors about that risk and encourage them to receive a recommended heart screening test.
Eligibility
Inclusion Criteria8
- Childhood Cancer Survivor Study (CCSS) Participants
- Age ≥26 years
- Treated with cumulative doxorubicin equivalent anthracycline doses ≥100 mg/m2 with any/no radiation, or ≥15 Gy chest radiation with any/no anthracyclines
- No history of cardiomyopathy
- Has not had an echocardiogram in the previous 5 years
- Has a history of successful completion of CCSS surveys
- English-Speaking
- Has not been enrolled in ECHOS-1 (pilot)
Exclusion Criteria1
- Currently participating in a long-term follow-up program that provides risk-based screening
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Interventions
Participants receive a personalized survivorship care plan and educational materials about cardiomyopathy risk and screening recommendations. Materials are delivered via the CIAS platform and include infographics, treatment summaries, and general information about screening.
Participants receive the same SOC materials plus a tailored, interactive eHealth intervention delivered via the CIAS platform. This includes avatar-led motivational interviewing (MI), survivor video vignettes, interactive modules addressing perceived barriers, self-efficacy, and goal setting. The intervention is designed to mimic MI counseling in a scalable format.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07245420