RecruitingNCT07247474

Triple EIT (Electrical Impedance Tomography)

Characterizing the Evolution of Neonatal Lung Disease Throughout Infancy and Childhood Using Electrical Impedance Tomography: A Pilot Study


Sponsor

University of Colorado, Denver

Enrollment

140 participants

Start Date

Jan 30, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study plans to learn more about ways to look at participant's lungs using new machines called Electrical Impedance Tomography (EIT). The EIT does not use harmful radiation like CT or x-ray. It is read through electrodes like using EKG reading heartbeats. The investigators want to compare the results of patients who have chronic respiratory disease to patients without chronic respiratory disease to learn more about lung structure and composition.


Eligibility

Min Age: 2 WeeksMax Age: 25 Years

Inclusion Criteria10

  • weeks to 25 years of age
  • evidence of cardiopulmonary disease including, but not limited to:
  • Post-prematurity respiratory disease
  • Congenital diaphragmatic hernia
  • Pulmonary Hypertension
  • Congenital heart disease
  • Respiratory failure
  • Neuromuscular Disease
  • Developmental or congenital lung disease
  • OR matched healthy controls (born at term gestation (\>36 weeks gestational age) with no cardiopulmonary disease)

Exclusion Criteria5

  • \<2 weeks of age
  • Anything that interferes with lead placement on the chest wall (such as, dermatologic conditions, multiple chest tubes, anatomic abnormality, or large dressings that cannot be moved)
  • No informed consent
  • Pregnant or lactating
  • Pacemaker or other metal intrathoracic surgical implant (causes noise in the data)

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Interventions

DEVICEElectrical impedance tomography (EIT)

Electrical impedance tomography (EIT) is a noninvasive and non-ionizing imaging technique that describes lung ventilation and perfusion


Locations(1)

Children's Hospital Colorado

Aurora, Colorado, United States

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NCT07247474


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