Cardiopulmonary Clinical Trials

3 recruiting

Frequently Asked Questions

Common questions about Cardiopulmonary clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 45 trials

Recruiting

Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

Healthy VolunteersEndothelial DysfunctionInflammation in Cardiopulmonary and Vascular Disease States
National Institutes of Health Clinical Center (CC)1,000 enrolled1 locationNCT03253705
Recruiting
Phase 3

Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

Complex Cardiovascular Surgery With Cardiopulmonary Bypass
CSL Behring200 enrolled19 locationsNCT07094087
Recruiting
Not Applicable

Effects of LPG and Ventilation Interventions on Reducing HAP and Improving Cardiopulmonary Health

Cardiopulmonary FunctionEnvironmental Exposures
Huazhong University of Science and Technology1,200 enrolled3 locationsNCT07005193
Recruiting

Risk and Resilience in Pulmonary Arterial Hypertension and Genetically Susceptible Individuals

Idiopathic Pulmonary Arterial HypertensionHeritable Pulmonary Arterial HypertensionUnaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo+1 more
Vanderbilt University Medical Center150 enrolled1 locationNCT05584722
Recruiting
Phase 2

Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients

Coronary Artery Bypass Grafting (CABG)Cardiopulmonary BypassIntensive Care Unit+9 more
GCP-Service International West GmbH550 enrolled10 locationsNCT06279793
Recruiting
Phase 1Phase 2

Influence of Lung Volume Optimization Maneuver in Ventilated Children on Cardiac Output and Lung Compliance in Children With Congenital Heart Disease Undergoing Surgical Repair and on Prevention of Need for ECMO or Shortening of ECMO Duration in Children With Severe Respiratory Failure

Mechanical VentilationCongenital Heart DiseaseChildren+8 more
Charite University, Berlin, Germany80 enrolled1 locationNCT07193719
Recruiting

Triple EIT (Electrical Impedance Tomography)

Neonates and Preterm InfantsCardiopulmonary
University of Colorado, Denver140 enrolled1 locationNCT07247474
Recruiting

GLS in Difficult CPB Weaning

Heart Valve DiseasesCoronary Artery BypassEchocardiography+3 more
Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital213 enrolled2 locationsNCT07390903
Recruiting

Prognosis of Patients With Mixed Cardiogenic-Vasoplegic Shock

Septic ShockMyocardial Infarction (MI)Mechanical Circulatory Support+3 more
Centre Hospitalier Universitaire, Amiens2,500 enrolled1 locationNCT07354568
Recruiting
Not Applicable

Safety and Performance Evaluation of CPB Venous and Arterial Cannulas

Heart SurgeryCardiac SurgeryCardiopulmonary Bypass+4 more
Eurosets S.r.l.80 enrolled1 locationNCT07354841
Recruiting
Not Applicable

Effect of Bed Height on Chest Compression Quality and Provider Biomechanics During Pediatric CPR Simulation

Pediatric Cardiac Arrest (Simulated)Cardiopulmonary Resuscitation, Simulation Training
Akdeniz University25 enrolled1 locationNCT07329842
Recruiting
Phase 2

Delayed Cold-Stored Platelets -PLTS-1

BleedingCardiac SurgeryCardiopulmonary Bypass+1 more
University Health Network, Toronto150 enrolled2 locationsNCT06147531
Recruiting

Observational, Non-Interventional Study Supporting Validation of VO2Max Estimation Methods Using Results in Patients Receiving Standard of Care Cardiopulmonary Exercise Tests (CPET)

Cardiopulmonary
Prolaio1,000 enrolled16 locationsNCT05678530
Recruiting

Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery

PneumothoraxLung UltrasoundCardiac Surgery+2 more
Jacobo Moreno Garijo120 enrolled1 locationNCT07018856
Recruiting

Hantavirus Registry - HantaReg

Hantavirus InfectionsHemorrhagic Fever With Renal SyndromeNephropathia Epidemica+1 more
University of Cologne200 enrolled1 locationNCT04323904
Recruiting
Not Applicable

Heart-Lung Machine: Impact of the Priming Solution on Acid-Base Balance, Electrolytes and Outcome on Patients Undergoing Cardiac Surgery

Cardiopulmonary BypassAcid Base ImbalanceOsmolality Disturbance+2 more
Region Skane80 enrolled1 locationNCT07267546
Recruiting
Phase 4

Rehabilitation for Survivors of Out-of-hospital Cardiac Arrest

Cardiopulmonary ResuscitationCardiac ArrestReturn to Work+1 more
Rigshospitalet, Denmark214 enrolled1 locationNCT05173740
Recruiting

Effective Myocardial Protection Time of Del Nido Cardioplegia in Adult Cardiac Surgery

Myocardial IschemiaHeart Valve DiseasesAortic Diseases+3 more
Muhammet Talha Ceran, MD80 enrolled1 locationNCT07249424
Recruiting
Not Applicable

Effects of Rope Skipping in Cardiopulmonary Fitness in Children

Cardiopulmonary
Riphah International University178 enrolled1 locationNCT07249671
Recruiting
Not Applicable

A Randomized Controlled Study of the NEURESCUE Device as an Adjunct to Advanced Cardiac Life Support

Cardiac Arrest (CA)Cardiopulmonary Arrest
neurescue84 enrolled2 locationsNCT06793033