Cardiopulmonary Clinical Trials

69 recruitingLast updated: July 25, 2026

There are 69 actively recruiting cardiopulmonary clinical trials across 31 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3. Top locations include Boston, Massachusetts, United States, Toronto, Ontario, Canada, Chicago, Illinois, United States. Updated daily from ClinicalTrials.gov.


Cardiopulmonary Trials at a Glance

69 actively recruiting trials for cardiopulmonary are listed on ClinicalTrialsFinder across 6 cities in 31 countries. The largest study group is Not Applicable with 25 trials, with the heaviest enrollment activity in Boston, Toronto, and Chicago. Lead sponsors running cardiopulmonary studies include Seoul National University Hospital, Mayo Clinic, and Assistance Publique - Hôpitaux de Paris.

Browse cardiopulmonary trials by phase

Treatments under study

About Cardiopulmonary Clinical Trials

Looking for clinical trials for Cardiopulmonary? There are currently 5 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cardiopulmonary trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cardiopulmonary clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 69 trials

Recruiting

Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies

Mortality in Sickle CellSickle Cell Cardiopulmonary ComplicationsSickle Cell Organ Damage+2 more
National Heart, Lung, and Blood Institute (NHLBI)200 enrolled1 locationNCT05213572
Recruiting
Phase 2

Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients

Coronary Artery Bypass Grafting (CABG)Cardiopulmonary BypassIntensive Care Unit+9 more
GCP-Service International West GmbH550 enrolled10 locationsNCT06279793
Recruiting
Not Applicable

COMPARE-VENT Feasibility Pilot Study

Cardiogenic ShockMechanical VentilationCritical Illness+4 more
Mayo Clinic75 enrolled1 locationNCT07656259
Recruiting

Ted Rogers Understanding of Exacerbations in Heart Failure 2: Monitor

Heart FailureHeart Failure - NYHA II - IVHeart Failure Patients+2 more
University Health Network, Toronto360 enrolled3 locationsNCT07447908
Recruiting
Not Applicable

CompaRison of FEmorofemoral Bypass and Left-Heart ByPass Techniques in Open Thoracoabdominal AortIc Aneurysm Repair

Cardiopulmonary BypassThoracoabdominal Aortic AneurysmOpen Repair
Beijing Anzhen Hospital236 enrolled1 locationNCT07518251
Recruiting
Not Applicable

Simulation Trial of Telemedical Support for Paramedics

Acute Respiratory FailureEmergenciesCardiopulmonary Arrest+1 more
Boston Medical Center420 enrolled9 locationsNCT06441760
Recruiting

HEMO-INTEGRA: Integrated Intraoperative Hemodynamic Monitoring During Cardiac Surgery With Cardiopulmonary Bypass - A Pilot Study

Hemodynamic MonitoringCardiac SurgeryCardiopulmonary Bypass+1 more
Hernán Darío Castro Arias30 enrolled1 locationNCT07683299
Recruiting

Lung and Heart Function Across Decades of Life in Health

DyspneaPollution; ExposurePollution Related Respiratory Disorder+1 more
University of California, San Francisco200 enrolled1 locationNCT07641413
Recruiting
Not Applicable

Preventive Narrative Exposure Intervention for PTSD in ICU Patients After Cardiopulmonary Bypass Cardiac Surgery

Stress Disorders, Post-TraumaticCardiopulmonary BypassIntensive Care Units
First Affiliated Hospital of Fujian Medical University100 enrolled1 locationNCT07632131
Recruiting
Phase 3

Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass

Cardiac SurgeryCardiopulmonary BypassNitric Oxide+1 more
Xijing Hospital3,650 enrolled3 locationsNCT06702553
Recruiting
Not Applicable

Effect of Different Breathing Techniques on Dyspnea and Cardiopulmonary Parameters Among Patients After Open Heart Surgery

DyspneaCoronary Artery DiseasePostoperative Respiratory Dysfunction+1 more
University of Baghdad99 enrolled3 locationsNCT07591987
Recruiting

Neutrophil Phenotypic Profiling and Acute Lung Injury in Patients After Cardiopulmonary Bypass (CPB)

Lung InjuryCardiopulmonary Bypass
Sophia Koutsogiannaki56 enrolled1 locationNCT04296071
Recruiting

PERCEPTION - Super-Early Neuroprognostication in eCPR Patients

ResuscitationECMOExtracorporeal Cardiopulmonary Resuscitation+1 more
Medical University of Vienna45 enrolled1 locationNCT07584187
Recruiting

Evaluation of Plasma Renin Concentrations in Cardiac Surgery

Cardiac surgery with cardiopulmonary bypass
Mayo Clinic100 enrolled1 locationNCT06895213
Recruiting
Phase 3

Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

Complex Cardiovascular Surgery With Cardiopulmonary Bypass
CSL Behring200 enrolled18 locationsNCT07094087
Recruiting

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

Opioid Induced Respiratory DepressionPostoperative Complications (Cardiopulmonary)Respiratory Complications Due to Anesthesia
NeurOptics Inc300 enrolled2 locationsNCT07573150
Recruiting

Effect of Hypothermia on BIS and PSI Correlation During Cardiopulmonary Bypass

Cardiopulmonary BypassHypothermia; AnesthesiaDepth of Anesthesia Monitoring
Sakarya University60 enrolled1 locationNCT07508579
Recruiting
Not Applicable

Compression Only CPR Versus Standard CPR in Out-Of-Hospital Cardiac Arrest - A Randomized Survival Study

Cardiopulmonary ResuscitationCardiac ArrestOut-of-hospital cardiac arrest
Karolinska Institutet3,260 enrolled2 locationsNCT03981107
Recruiting
Not Applicable

Evaluation of Mixed Reality Cardiopulmonary Resuscitation Training

Cardiopulmonary resuscitation (CPR)Cardiac Arrest (CA)Basic Life Support Training Course
Seoul National University Hospital120 enrolled1 locationNCT07363772
Recruiting

Samples From Human Subjects to Facilitate Basic, Translational and Clinical Research

Healthy VolunteersEndothelial DysfunctionInflammation in Cardiopulmonary and Vascular Disease States
National Institutes of Health Clinical Center (CC)1,000 enrolled1 locationNCT03253705