Comparison of Patients With COPD and PRISM
Comparison of Respiratory and Peripheral Muscle Strength, Exercise Capacity, and Muscle Oxygenation in Individuals With COPD and PRISM
Karabuk University
60 participants
Oct 5, 2025
OBSERVATIONAL
Conditions
Summary
COPD is a preventable and treatable lung disease characterized by persistent and progressive airflow limitation. PRISm, on the other hand, is a spirometry pattern that does not meet COPD diagnostic criteria despite symptoms and functional impairments, but requires maintenance. PRISm can predispose to the development of COPD and exacerbations, and can reduce exercise capacity by reducing respiratory function and oxygen consumption. There are no studies in the literature comparing respiratory muscle strength, peripheral muscle strength, and oxygenation in PRISm, COPD, and healthy individuals. Therefore, this study aimed to evaluate these parameters and compare them with healthy individuals.
Eligibility
Inclusion Criteria12
- For the COPD group:
- Being \>40 years old,
- Being diagnosed with COPD,
- Being clinically stable,
- Volunteering to participate in the study.
- For the PRISm group:
- Being \>40 years old,
- Being diagnosed with PRISm,
- Volunteering to participate in the study.
- For the healthy control group:
- Being \>40 years old,
- Volunteering to participate in the study.
Exclusion Criteria14
- For the COPD group:
- Having severe orthopedic, neurological, or cardiac diseases,
- Being in a COPD exacerbation,
- Having a comorbid lung disease,
- Being on clinically unstable medication,
- Voluntarily not participating in the study.
- For the PRISm group:
- Being diagnosed with COPD,
- Having severe orthopedic, neurological, or cardiac diseases,
- Having a comorbid lung disease,
- Voluntarily not participating in the study.
- For the healthy control group:
- Having a known chronic disease,
- Voluntarily not participating in the study.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07249567