Comparison of Patients With COPD and PRISM

This study compares patients with COPD (chronic obstructive pulmonary disease), patients with a condition called PRISm (Preserved Ratio Impaired Spirometry, a pre-COPD breathing abnormality), and healthy individuals to better understand the differences in their physical function and health status. It is an observational study. **You may be eligible if...** - You are over 40 years old - You have a diagnosed with COPD (and are currently clinically stable, not in a flare-up), OR - You have been diagnosed with PRISm, OR - You are a healthy person with no known chronic disease - You are willing to voluntarily participate **You may NOT be eligible if...** - You have a COPD flare-up at the time of the study - You have severe orthopedic, neurological, or heart problems - You have any other lung disease in addition to your COPD or PRISm - You are on unstable medications - COPD patients who are diagnosed with PRISm (and vice versa) are not eligible for the other group Talk to your doctor to see if this trial is right for you.