AI-assisted Endoscopic Ultrasound Grading of Early Esophageal Cancer Invasion Depth: A Multicenter, Prospective, Randomized Cohort Study

This study uses AI-assisted endoscopic ultrasound (a camera-based scan done through the mouth) to better determine how deeply early esophageal cancer has invaded the wall of the esophagus. Accurate staging before treatment can help doctors choose between endoscopic removal versus surgery. **You may be eligible if...** - You are 18 or older - You are undergoing endoscopic examination and have records and pathology reports - You have esophageal abnormalities such as an ulcer, low-grade or high-grade abnormal cells, squamous cell cancer, white patches, or polyps in the esophagus - You agree to participate in the study **You may NOT be eligible if...** - You have already had surgery for esophageal cancer - You have previously received radiation or chemotherapy for esophageal cancer - Key data from your records is missing Talk to your doctor to see if this trial is right for you.