RecruitingNCT07252986

Clinical Translation Research on a Multi-omics Breast Cancer Distant Metastasis Prediction Model Empowered by Artificial Intelligence

A Multi-omics Breast Cancer Distant Metastasis Prediction Model Empowered by Artificial Intelligence and Its Clinical Translation Research


Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Enrollment

2,000 participants

Start Date

Dec 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Breast cancer is one of the most common malignancies in women worldwide, and distant metastasis is the main cause of poor prognosis and death. This project aims to construct a precision prediction system based on multi-omics (digital pathology, immunohistochemistry, proteomics, gene sequencing) and artificial intelligence to predict distant and organ-specific metastasis (bone, lung, liver, brain) in breast cancer, analyze its mechanisms, and provide new solutions for precision medicine.


Eligibility

Sex: FEMALE

Plain Language Summary

Simplified for easier understanding

This study uses artificial intelligence (AI) combined with multi-omics data (genetic, protein, and other biological markers) from breast cancer tissue and blood samples to build a model that predicts which patients are at risk of their breast cancer spreading to distant organs such as the liver, bone, lung, or brain. **You may be eligible if...** - You are a female patient with a pathological diagnosis of breast cancer - Your diagnosis occurred at a participating hospital between January 2000 and December 2028 - You have developed distant metastases (spread to liver, bone, lung, or brain), AND your tissue samples from the primary tumor or metastatic site are stored at the participating hospital - Complete clinical information is available **You may NOT be eligible if...** - You have a metastatic cancer from a different primary origin (not breast cancer) - Your clinical information is incomplete Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

The Second Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

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NCT07252986


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