Effect of Omega-3 Fatty Acids on Eye Blood Vessels in Type 1 Diabetes
Role of Omega-3 Fatty Acids in Modulating Retinal Microvascular Changes in Type 1 Diabetes
University of Faisalabad
80 participants
Oct 1, 2025
INTERVENTIONAL
Conditions
Summary
The aim of this clinical trial is to learn if omega-3 fatty acid supplements help maintain healthy blood vessels in the eyes of adults with type 1 diabetes. It will also learn about the safety of omega-3 supplements. The main questions it aims to answer are: Do omega-3 supplements improve the health of retinal blood vessels in adults with type 1 diabetes? Are there any side effects when taking omega-3 supplements? Researchers will compare participants taking omega-3 supplements to a control group (if applicable) to see if the supplements help support retinal blood vessel health. Participants will: Take a daily omega-3 supplement for the duration of the study Attend regular eye exams to monitor changes in the retina Report any side effects or health changes during the study
Eligibility
Inclusion Criteria1
- Diagnosis of Type 1 Diabetes Age between 10 and 45 years Duration of diabetes ≥ 2 years Mild to moderate diabetic retinopathy allowed (based on fundus examination)
Exclusion Criteria1
- Presence of any ocular disease other than diabetic retinopathy Use of medications that may affect retinal vascular measurements or visual function outcomes Presence of systemic diseases other than diabetes (e.g., uncontrolled hypertension, autoimmune diseases) History of ocular surgery within the past 6 months Current participation in another interventional clinical trial
Interventions
Arm 1 - Omega-3 Supplement Group: Intervention Type: Dietary Supplement Intervention Name: Omega-3 Fatty Acid Supplement Intervention Description: Participants will take one daily capsule containing 1000 mg of combined EPA and DHA. The supplement is taken orally with food. Eye exams will be performed every three months to monitor retinal blood vessel health. Participants will report any side effects such as mild stomach upset. Arm 2 - Placebo / Control Group: Intervention Type: Placebo Intervention Name: Placebo Capsule Intervention Description: Participants will take a daily capsule that looks identical to the omega-3 supplement but contains no active omega-3 fatty acids. Eye exams will be performed every three months to monitor retinal blood vessel health. Participants will report any health changes.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07255326