RecruitingNot ApplicableNCT07256119

Evaluation of the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients


Sponsor

Ain Shams University

Enrollment

40 participants

Start Date

Aug 6, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

the purpose of this study is to evaluate the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 75 Years

Inclusion Criteria3

  • Women aged ≥18 years.
  • Histologically confirmed invasive, early-stage breast carcinoma scheduled for adjuvant radiotherapy.
  • Receiving total radiation dose of 40 Gy for 15 sessions.

Exclusion Criteria7

  • Prior exposure to radiotherapy.
  • Inflammatory or metastatic breast carcinoma.
  • Patients with connective tissue disorders.
  • Patients with skin inflammatory diseases (e.g. ectopic dermatitis).
  • Patients with known allergy or hypersensitivity to alpha lipoic acid.
  • Concomitant use of nonsteroidal anti-inflammatory drugs, corticosteroids, or antioxidant medications.
  • Patients who will fail to sign the written consent.

Interventions

DIETARY_SUPPLEMENTAlpha Lipoic Acid

alpha lipoic acid 300 mg three times daily under the trade name of THIOTACID manufactured by EVAPHARMA.


Locations(1)

Zagazig University Hospitals

Zagazig, Egypt

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07256119


Related Trials