Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease
Family Study of Early Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease
King's College London
200 participants
Aug 15, 2025
OBSERVATIONAL
Conditions
Summary
The goal of this project is to measure the prevalence of Autosomal Dominant Polycystic Kidney Disease (ADPKD) and hypertension in the general population of children and young people at risk of ADPKD, using magnetic resonance imaging (MRI) for rapid diagnosis alongside genetic testing. The main question it aims to answer is: What is the prevalence of hypertension in a population sample of adolescents with ADPKD? Participants will have the following measurements performed: * Height and weight. * Blood pressure. * Non-invasive measurement of arterial stiffness. * Cardiac and renal MRI. * Blood sample. * Genetic testing.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Locations(1)
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NCT07260071