RecruitingNot ApplicableNCT07261423

Pollution Intervention to Impact Kids Asthma Study

Sponsor

University of Pittsburgh

Enrollment

351 participants

Start Date

Feb 24, 2026

Study Type

INTERVENTIONAL

Conditions

Childhood Asthma Asthma Control Asthma Exacerbation Air Pollution, Risk Reduction Behaviors

Summary

The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are: * Does adding either information about the EPA-AQI or commercial AQI improve asthma outcomes over time? * Are there changes in nasal gene expression in children with asthma who report they are more sensitive to outdoor air pollution? Researchers will compare EPA-AQI and the commercial-AQI groups to a control group to either AQI works to improve asthma. Participants will: * Receive standardized outdoor air pollution education and an asthma action plan * Provide nose and blood specimens * Have visits every 4 weeks for 48 weeks, 10 will be conducted by telephone calls and 3 visits will be in person.

Eligibility

Min Age: 8 YearsMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether using air purifiers at home can reduce asthma attacks in children with persistent asthma who live in the Pittsburgh, Pennsylvania area. **You may be eligible if...** - Your child has been diagnosed with persistent asthma by a healthcare provider, OR has intermittent asthma AND had at least one severe asthma attack requiring steroids or an ER visit in the past 12 months - You have access to a smartphone or internet - Your child's primary residence is in Allegheny County, Pennsylvania **You may NOT be eligible if...** - Your child does not meet the asthma severity criteria - You do not live in the eligible geographic area - You cannot access the digital tools required for the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALEPA-AQI

The EPA-AQI group will receive standardized outdoor air pollution education, standardized AQI education, instructions for AQI usage, and an asthma action plan containing information specific for the EPA-AQI, and will demonstrate the ability to navigate to the EPA-AQI via smartphone app or website.

BEHAVIORALCommerical-AQI

The commercial-AQI group will receive standardized AQI education, instructions for commercial-AQI usage, and an asthma action plan containing information specific for the commercial-AQI, and will demonstrate the ability to navigate to the commercial-AQI via smartphone or website.

BEHAVIORALEducation and plan

Standardized outdoor air pollution education and standard asthma action plan