RecruitingNot ApplicableNCT07261956

Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia

Usefulness of Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia


Sponsor

Saint Thomas Hospital, Panama

Enrollment

202 participants

Start Date

Aug 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This research aims to evaluate the usefulness of lung ultrasound (LUS) for detecting and monitoring fluid overload in patients with severe preeclampsia. Severe preeclampsia is a leading cause of maternal death and illness worldwide, often causing fluid buildup that can lead to a serious complication called pulmonary edema, especially after delivery. The study will be a prospective, longitudinal observational study with a diagnostic validation component. It will involve patients with a diagnosis of severe preeclampsia who meet specific inclusion criteria. Each participant will undergo a clinical exam and a lung ultrasound, which will assess eight zones of the lungs. The total number of B-lines-a sign of interstitial edema-will be documented. Data will be collected at three key times: upon admission, in the immediate postpartum period (within 24 hours of delivery), and 7-10 days postpartum. The results from the LUS will be compared to clinical signs like shortness of breath, rapid breathing, crackling sounds in the lungs, and oxygen saturation levels. The expected impact of this research is to provide evidence that LUS is a valuable, non-invasive, and accessible tool for the early detection of pulmonary congestion in patients with severe preeclampsia. This could lead to improved clinical decision-making and a reduction in maternal respiratory complications.


Eligibility

Sex: FEMALE

Plain Language Summary

Simplified for easier understanding

This study is using lung ultrasound (a safe imaging technique using sound waves) to detect fluid overload — too much fluid building up in the lungs — in pregnant women admitted to hospital with severe preeclampsia, a dangerous complication of pregnancy involving high blood pressure. **You may be eligible if...** - You are between 24 and 41 weeks pregnant - You have been diagnosed with preeclampsia with severe features **You may NOT be eligible if...** - You have a chronic lung disease - You have a known heart condition - You already have pulmonary edema (fluid in the lungs) at the time of admission - Your BMI is above 40 - You need immediate delivery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIAGNOSTIC_TESTLung ultrasound

Lung ultrasounf at three moments (at admission, before delivery and immediate post partum) to determine B Lines


Locations(1)

Saint Thomas Hospital

Panama City, Provincia de Panamá, Panama

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07261956


Related Trials