RecruitingNCT07263204

AI-Enabled Diagnosis and Prognosis of Hypertrophic Cardiomyopathy

Precision Diagnosis and Prognostic Prediction of Hypertrophic Cardiomyopathy Using Artificial Intelligence: A Multicenter Study


Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Enrollment

15,000 participants

Start Date

Jan 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

By harnessing artificial intelligence to decode the 12-lead electrocardiogram, the project will enable precise ECG-based phenotyping of hypertrophic cardiomyopathy-accurately classifying septal, apical, and other morphologic subtypes-while simultaneously differentiating HCM from hypertensive heart disease, aortic stenosis, and other phenocopy disorders.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Adults aged ≥ 18 years.
  • HCM cohort: Adults diagnosed with hypertrophic cardiomyopathy in accordance with the \*2023 Chinese Guidelines for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy in Adults\*.
  • HCM phenocopy cohort: Adults with an LV wall thickness ≥ 13 mm at any site on echocardiography.
  • Healthy-control cohort: Adults with no history of cardiac disease and no evidence of myocardial hypertrophy on echocardiography.

Exclusion Criteria1

  • Patients from whom analyzable ECG data cannot be obtained.

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Locations(1)

Second Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

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NCT07263204


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