RecruitingNCT07054073

HCMR Re-Imaging Study


Sponsor

Christopher Kramer

Enrollment

314 participants

Start Date

Mar 30, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to learn what might predict heart problems (like sudden death from a fast heart rhythm or heart failure) in people with a genetic condition called hypertrophic cardiomyopathy (HCM). HCM causes the heart muscle to become thick, which can make the heart stiff and harder to work properly. It can also affect the heart's electrical system. This study is looking to enroll patients that were previously part of a research project called "HCMR - Novel Predictors of Outcome in Hypertrophic Cardiomyopathy." The results of that study are still being reviewed, but they might show that people who had a substance called Gadolinium (MRI contrast or dye) collected in their heart muscle may have a higher risk for heart problems, including sudden cardiac death. This is called "late gadolinium enhancement" (LGE). This study is aiming to do follow-up imaging on those patients to better understand how LGE affects people with HCM.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying None - observational study for people with hypertrophic cardiomyopathy (hcm). The study is currently recruiting participants at 8 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERNone - observational study

None - observational study


Locations(8)

Northwestern

Evanston, Illinois, United States

Brigham & Women's Hospital

Boston, Massachusetts, United States

Tufts Medical Center

Medford, Massachusetts, United States

University of Michigan

Ann Arbor, Michigan, United States

Cleveland Clinic

Cleveland, Ohio, United States

University of Virginia

Charlottesville, Virginia, United States

University Hospitals Birmingham NHS Foundation Trust

Birmingham, United Kingdom

London Chest Hospital

London, United Kingdom

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NCT07054073


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