RecruitingPhase 1Phase 2NCT07464132

Application of [68Ga]Ga-NI-FAPI-04 PET/CT Imaging in Fibroblast Activation Protein Related Diseases


Sponsor

Peking Union Medical College Hospital

Enrollment

30 participants

Start Date

Dec 17, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to conduct clinical research on \[68Ga\] Ga-NI-FAPI-04 PET/CT imaging and further investigate its diagnostic value in fibroblast activation related diseases.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new PET/CT imaging agent called [68Ga]Ga-NI-FAPI-04 that targets activated fibroblast cells, which are found in large numbers in many cancers and inflammatory conditions. Researchers want to see how well this scan detects cancer and other fibroblast-related diseases compared to existing imaging methods. **You may be eligible if...** - You are between 18 and 85 years old - You have a cancer that can be confirmed by surgery or biopsy - You are expected to survive at least 6 months and can attend follow-up visits - You are a healthy volunteer with no chronic medical conditions (for the control group) **You may NOT be eligible if...** - You are pregnant or breastfeeding - You are allergic to any component of the imaging drug - You have severe liver or kidney problems - You are participating in another clinical trial that could interfere - You are too unwell to cooperate with the scan Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGInjection of 68Ga-NI-FAPI

Subjects were injected with 68Ga-NI-FAPI at 0.4-0.5mci/kg body weight


Locations(1)

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

Beijing, Beijing Municipality, China

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NCT07464132


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