Safety and Feasibility of IRE for Early-stage Breast Cancer: a Prospective, Open-Label, Single-Arm, Exploratory Study

This study is evaluating the safety and feasibility of irreversible electroporation (IRE) — a non-thermal energy-based technique that destroys cancer cells using electrical pulses without heat — as an alternative to surgery for small, early-stage breast cancers. **You may be eligible if...** - You are female and 18 or older - You have a confirmed diagnosis of invasive ductal carcinoma (IDC) — the most common type of breast cancer — within the past 3 months - Your tumor is 2 cm or smaller and is clearly visible on both ultrasound and MRI - You have not received any prior breast cancer treatment - You are medically fit for both surgery and general anesthesia **You may NOT be eligible if...** - Your tumor is larger than 2 cm or is multifocal (in multiple areas) - You have received prior treatment for this breast cancer - You have a pacemaker or other implanted device sensitive to electrical fields - Your tumor is not clearly visible on imaging Talk to your doctor to see if this trial is right for you.