RecruitingPhase 1NCT07264270

Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy

A Phase 1, Randomized, Double-Blind, Single Dose Escalation Study to Assess the Safety and Tolerability of Transforaminal Epidural Administration of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy

Sponsor

Consano Bio

Enrollment

24 participants

Start Date

Dec 3, 2025

Study Type

INTERVENTIONAL

Conditions

Lumbosacral Radiculopathy Sciatica Sciatic Radiculopathy Lumbosacral Radicular Pain Sciatic Leg Pain Lumbosacral Radicular Syndrome

Summary

The purpose of this study is to evaluate the safety and tolerability of C-1101 administered as a single dose, transforaminal epidural injection compared to sterile saline

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called C-1101 and Placebo: Sterile Saline for people with lumbosacral radicular pain, lumbosacral radicular syndrome, and other related conditions. The study is currently recruiting participants at 3 locations. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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