Sciatica Clinical Trials

13 recruiting

Frequently Asked Questions

Common questions about Sciatica clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Phase 1

Study to Evaluate Safety of C-1101 Versus Sterile Saline in Adults With Chronic Painful Lumbosacral Radiculopathy

Lumbosacral RadiculopathySciaticaSciatic Radiculopathy+3 more
Consano Bio24 enrolled3 locationsNCT07264270
Recruiting
Not Applicable

FINDISC-Pain, Finnish Discectomy Trial on the Benefits and Harms of Surgery in Patients With Lumbar Disc Herniation

SciaticaLumbar Disc Herniation With Radiculopathy
Helsinki University Central Hospital122 enrolled1 locationNCT07418944
Recruiting
Not Applicable

A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE

Lumbosacral RadiculopathySciaticaRadiculopathy Lumbar+2 more
National University of Natural Medicine32 enrolled1 locationNCT07125027
Recruiting

Total Lumbar Disc Prosthesis and Subsequent Work Activity at at Least Five Years After Total Lumbar Disc Replacement

SciaticaLumbar Disc HerniationLumbar Disc Degeneration+2 more
University of Valencia150 enrolled1 locationNCT06989632
Recruiting
Not Applicable

Comparing the Efficacy of Steroid, Acupuncture and Platelet Rich Plasma Injection in Patients with Sciatica

Sciatica
Taipei Medical University Hospital90 enrolled1 locationNCT03801512
Recruiting
Not Applicable

Effects of Myofacial Release Technique and Sciatic Nerve Slider Technique in Sciatica

SciaticaSciatic Neuropathy
Riphah International University36 enrolled1 locationNCT06536829
Recruiting
Phase 4

Duloxetine for chronic sciatica (DREAM): an adaptive randomised placebo-controlled trial

Sciatica
The University of Sydney332 enrolled1 locationACTRN12624000919516
Recruiting
Not Applicable

Transforaminal Epidural Injection in Acute Sciatica

SciaticaSciatica Due to Intervertebral Disc DisorderSciatic Radiculopathy
C.L.A.Vleggeert-Lankamp142 enrolled2 locationsNCT03924791
Recruiting
Phase 4

Oral steroids in sciatica: The OASIS Randomised Controlled Trial

Sciatica
The University of Sydney200 enrolled1 locationACTRN12619001716156