RecruitingNCT07264959

An Observational Study in Participants With Indolent Systemic Mastocytosis (ISM)

An Observational Study in Patients With Indolent Systemic Mastocytosis


Sponsor

Blueprint Medicines Corporation

Enrollment

150 participants

Start Date

Apr 15, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This is a Phase 4, non-interventional, observational study to collect detailed data on the clinical characteristics, clinical outcomes and medical management of ISM in real-world settings. The study will describe the demographic and clinical characteristics of ISM participants, including anaphylaxis and bone manifestations in ISM. Quality of life and disease control will be assessed through participant questionnaires. The study will also evaluate real world ISM treatment management, including use of avapritinib.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with indolent systemic mastocytosis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Brigham and Women's Allergy and Clinical Immunology, Mass General Brigham Healthcare Center (Chestnut Hill)

Chestnut Hill, Massachusetts, United States

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NCT07264959


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