RecruitingNCT07265388

SUCCESS Score Validation in Fuchs Dystrophy

Validation and Extension of the SUCCESS Score for Fuchs Dystrophy After Cataract Surgery

Sponsor

Instituto Ramón y Cajal de Investigación Sanitaria

Enrollment

250 participants

Start Date

Jun 1, 2020

Study Type

OBSERVATIONAL

Conditions

Fuchs' Endothelial Corneal Dystrophy

Summary

This prospective multicenter diagnostic study aims to externally validate and extend the SUCCESS Score for predicting the need for endothelial keratoplasty after cataract surgery in patients with Fuchs endothelial corneal dystrophy (FECD). The model's performance and clinical utility are assessed using discrimination, calibration, and reclassification metrics.

Eligibility

Min Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Phacoemulsification Cataract Surgery for people with fuchs' endothelial corneal dystrophy. The study is currently recruiting participants at 1 location. People eligible for this study include aged 40 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREPhacoemulsification Cataract Surgery

Standard phacoemulsification cataract surgery performed in patients with Fuchs endothelial corneal dystrophy (FECD). All procedures are carried out according to institutional protocols at participating tertiary centers. Preoperative Scheimpflug tomography and corneal densitometry measurements are collected to calculate the SUCCESS Score and evaluate the risk of postoperative endothelial decompensation. Postoperative outcomes are monitored to determine whether endothelial keratoplasty (EK) is required during follow-up.