Fuchs' Endothelial Corneal Dystrophy Clinical Trials

7 recruitingLast updated: May 21, 2026

There are 7 actively recruiting fuchs' endothelial corneal dystrophy clinical trials across 6 countries. Studies span Phase 2, Not Applicable. Top locations include Boston, Massachusetts, United States, Grand Rapids, Michigan, United States, Heidelberg, Germany. Updated daily from ClinicalTrials.gov.


Fuchs' Endothelial Corneal Dystrophy Trials at a Glance

7 actively recruiting trials for fuchs' endothelial corneal dystrophy are listed on ClinicalTrialsFinder across 6 cities in 6 countries. The largest study group is Phase 2 with 2 trials, with the heaviest enrollment activity in Boston, Grand Rapids, and Heidelberg. Lead sponsors running fuchs' endothelial corneal dystrophy studies include Design Therapeutics, Inc., Eye & ENT Hospital of Fudan University, and Centre Hospitalier Régional Metz-Thionville.

Browse fuchs' endothelial corneal dystrophy trials by phase

About Fuchs' Endothelial Corneal Dystrophy Clinical Trials

Looking for clinical trials for Fuchs' Endothelial Corneal Dystrophy? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Fuchs' Endothelial Corneal Dystrophy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Fuchs' Endothelial Corneal Dystrophy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Not Applicable

Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK)

Descemet Membrane Endothelial Keratoplasty (DMEK)Fuchs' Endothelial Corneal Dystrophy
University Hospital Heidelberg102 enrolled1 locationNCT07373821
Recruiting
Phase 2

DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal DystrophyFuchs
Design Therapeutics, Inc.28 enrolled2 locationsNCT07024693
Recruiting

SUCCESS Score Validation in Fuchs Dystrophy

Fuchs' Endothelial Corneal Dystrophy
Instituto Ramón y Cajal de Investigación Sanitaria250 enrolled1 locationNCT07265388
Recruiting
Phase 2

Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy

Fuchs' Endothelial Corneal Dystrophy
Massachusetts Eye and Ear Infirmary45 enrolled1 locationNCT04440280
Recruiting

Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With Cataracts

CataractFuchs' Endothelial Corneal Dystrophy
Eye & ENT Hospital of Fudan University120 enrolled1 locationNCT06966167
Recruiting

FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United Kingdom

Corneal DystrophyFuchs' Endothelial DystrophyFuchs Dystrophy+2 more
University College, London500 enrolled1 locationNCT06881771
Recruiting

Prognosis of Posterior Lamellar Keratoplasty, an Observational Cohort Study

Pseudophakic Bullous KeratopathyFuchs' Endothelial Corneal Dystrophy
Centre Hospitalier Régional Metz-Thionville1,000 enrolled1 locationNCT06859411