RecruitingNot ApplicableNCT07266259

Effect of Levocarnitine Plus Myoinositol Versus Myoinositol Alone on Hormonal and Insulin Resistance in PCOS Women

Effects of Levocarnitine and Myoinositol in Comparison to Myoinositol Alone on Hormonal and Insulin Resistance Parameters in Subfertile Women With Insulin Resistant Polycystic Ovary Syndrome

Sponsor

Mst.Sumyara Khatun

Enrollment

72 participants

Start Date

Sep 19, 2025

Study Type

INTERVENTIONAL

Conditions

Polycystic Ovary Syndrome (PCOS)

Summary

The goal of this clinical trial is to learn if combination of levocarnitine and myoinositol works better than myoinositol alone on insulin resistance and hormonal parameters in subfertile women with insulin resistant polycystic ovary syndrome . It will also learn about the safety of drug levocarnitine and myoinositol. The main questions it aims to answer are: Does combined action of levocarnitine and myoinositol improve insulin resistance and hormonal parameters in comparison to myoinositol alone in subfertile women with insulin resistant polycystic ovary syndrome ? What medical problems do participants have when taking drug levocarnitine and myoinositol? Researchers will compare the drug combination of levocarnitine and myoinositol to myoinositol alone to see if combination therapy works better? Participants will: Take drug levocarnitine and myoinositol or a myoinositol alone twice daily for 3 months Visit the clinic once after 3 months for checkups and tests Keep a diary of their symptoms and the number of times.

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two supplement combinations — levocarnitine plus myoinositol versus myoinositol alone — to see which works better at improving hormone balance and reducing insulin resistance in women with polycystic ovary syndrome (PCOS) who are having trouble getting pregnant. **You may be eligible if...** - You are between 18 and 40 years old - You have been diagnosed with PCOS according to current international guidelines - You are experiencing difficulty getting pregnant (primary or secondary infertility) - You have insulin resistance (measured by a test called HOMA-IR greater than 2.6) **You may NOT be eligible if...** - You have an underactive thyroid (hypothyroidism) - You have diabetes - You have taken myoinositol, D-chiro-inositol, or insulin-sensitizing medications like metformin or pioglitazone in the past 3 months - You have a known allergy to myoinositol or levocarnitine - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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