Betamethasone Phonophoresis For Vitiligo
Effect of Betamethasone Phonophoresis in Treatment of Vitiligo
Cairo University
60 participants
Nov 10, 2025
INTERVENTIONAL
Conditions
Summary
Vitiligo is a skin disorder that results in the formation of depigmented patches or hypopigmented macules due to selective destruction or reduction of melanocytes the cells that produce pigment in our skin. Vitiligo affects 0.1-2% of the World's population. People of all skin types and all ages can be affecte. In most of the cases, white patches develop or expand slowly overtime, and in some cases it never progress and remains stable . Vitiligo can be segmental or non-segmental depending upon the morphology of the clinical involvement. It can also be classified as stable or unstable based on the activity of disease. Steroids act as anti-inflammatory and immunosuppressant agents. Even if different classes of steroids are now available, the mid- potent ones (e.g. betamethasone dipropionate 0.05% cream, 0.05% clobetasol propionate ointment) are usually preferred for the treatment of young patients . Now days, topical corticosteroids are the most commonly prescribed agents in treatment of dermatologic conditions .Almost all treatments of vitiligo have borrowed from therapies whose prime targets have been another disease.
Eligibility
Inclusion Criteria5
- Male and female patients diagnosed with vitiligo.
- Medically and psychologically stable patients.
- Good cognitive abilities to understand the requirements of the study.
- All patients enrolled to the study will have their informed consent.
- they had no contraindications to the use of therapeutic ultrasound
Exclusion Criteria9
- Pregnancy or lactation.
- Immunosuppression.
- Alcohol abuse.
- History of spontaneous re-pigmentation of lesions.
- Presence of skin characteristics that may interfere with study assessment.
- Active bacterial/viral infection.
- Patients on other immune suppressants and phototherapy
- Patients currently participating in any other clinical study
- Uncooperative patients.
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Interventions
to determine the effect of betamethasone phonophoresis on vitiligo patients.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07267273