Treating Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: Ablation or Medication

This study is comparing catheter ablation (a procedure that uses heat or cold to destroy abnormal heart tissue) versus medication alone for treating atrial fibrillation (AFib) in patients who also have a type of heart failure where the heart pumps normally but is stiff (called HFpEF). Both AFib and HFpEF are common together and can worsen each other. **You may be eligible if...** - You are 18 or older - You have atrial fibrillation confirmed by an ECG, Holter monitor, or rhythm strip - You have moderate heart failure symptoms (NYHA class II or III) - Your heart's pumping function is above 40% - You meet specific lab marker thresholds for heart failure (NT-proBNP levels) **You may NOT be eligible if...** - You have had a prior catheter ablation for AFib - Your heart failure is very severe (NYHA class IV) - You have a pacemaker or defibrillator that would interfere with ablation - You have significant valve disease requiring surgery - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.