Adrenaline V/s Dopamine in Fuid Refractory Septic Shock
Comparison of the Efficacy of Renaline and Dopamine in the Treatment of Fluid Refractory Septic Shock in Children
Laiba Qamar
90 participants
Jun 1, 2025
INTERVENTIONAL
Conditions
Summary
This study compares the efficacy of two drugs i.e Adrenaline and dopamine in fluid refractory type of septic shock which is a dreadful medical condition especially in children. The efficacy will be checked based on heart rate , GCS, capillary refill time , palpable pripheral pulse , urine output and systolic blood pressure.
Eligibility
Inclusion Criteria2
- Patients of both Genders having age range between 1month and 12 years with diagnosis of fluid refractory septic shock as per operational definition.
- \-
Exclusion Criteria6
- Patients with
- cardiopumonary Bypass during last 5 days
- Chronic Systemic disease like Chronic kidney Disease , cerebral palsy, congenital heart disease
- neuromuscular discorder
- Metabolic disorders
- Those who already had treatment at periphery for hypovolemia without any record of medication or sequential organ failure at presentation
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Interventions
The adrenaline will be given as a vasoconstrictor in the dose of 0.1-0.3ug/kg/min to the patients in group A when diagnosed with fluid refractory septic shock
The drug dopamine will be adminitered in dose of 10-20ug/kg/min to the patients of group B when diagnosed with fluid refractory septic shock.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07273526