Infants With Primary Congenital Hypothyroidism and Development
Investigation of Development Infants With Primary Congenital Hypothyroidism
Nigde Omer Halisdemir University
40 participants
Dec 20, 2025
OBSERVATIONAL
Conditions
Summary
A review of the literature has focused primarily on the cognitive and motor development of children with congenital hypothyroidism, but no studies on sensory processing skills have been found. Considering the age range of the groups studied, studies conducted in the early stages of life are rare. This planned study aims to examine the neurological status, motor development, and sensory processing skills of infants aged 6-18 months, considering early synaptogenesis.
Eligibility
Inclusion Criteria3
- Those with primary congenital hypothyroidism who have been treated since the newborn period and are currently on treatment.
- Infants born at term.
- Between 6 and 18 months old.
Exclusion Criteria5
- Infants with secondary congenital hypothyroidism,
- Preterm infants,
- Those with congenital infections or proven genetic alterations,
- Infants diagnosed with metabolic, neurological, or genetic diseases,
- Infants whose parents did not volunteer for the study
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
The Hammersmith Infant Neurological Examination (HINE) was planned to be used to assess the neurological status of infants. The HIND is a standardized examination for children aged 3 to 24 months, with high predictive value in the early detection of neurological disorders.
The Test of Sensory Function in Infants (TSFI) was planned to be used to assess infant sensory development. The TSFI is frequently used to assess the sensory processing functions of infants aged 4-18
The Peabody Developmental Motor Scales-2 (PDMS-2) was planned to be used to assess motor development. The test is designed to identify developmental delays in children aged 0-72 months.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07280104