The Synergistic Effects of Menopause and HIV on Cardiovascular Disease Risk in Women
University of California, San Francisco
90 participants
Apr 17, 2026
OBSERVATIONAL
Conditions
Summary
Menopause is associated with the acceleration of many comorbidities, including cardiovascular disease. Whether HIV and menopause together increase cardiovascular disease risk is a key knowledge gap. The goal of this observational study is to address this knowledge gap by looking at the role of menopause on cardiovascular disease risk factors such as insulin resistance, hypertension, hyperlipidemia, and carotid atherosclerosis using previously collected data. The investigators will look at underlying causes for cardiovascular diseases worsening in menopausal women with HIV by looking at the role of increased inflammation in the body and whether this is altered by weight. The investigators achieve this by enrolling participants who are willing to undergo a whole body MRI.
Eligibility
Inclusion Criteria1
- non-pregnant women with HIV (approximately 30 in each menopausal phase) from the San Francisco MWCCS site.
Exclusion Criteria4
- Women who are not virally suppressed (HIV RNA >200 copies/mL)
- Women who are not on antiretroviral therapy
- Women who have a history of hysterectomy or oophorectomy
- Women who are receiving treatment for active cancer or tuberculosis
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Whole body MRI will be performed as part of a study protocol
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07284082