RecruitingEarly Phase 1NCT07290205

Remimazolam NeuroImaging

Neuroimaging of Sedation With Remimazolam

Sponsor

Keith M Vogt

Enrollment

60 participants

Start Date

Mar 27, 2026

Study Type

INTERVENTIONAL

Conditions

Pain Anesthesia Remimazolam

Summary

This is a single-arm functional MRI study that will determine the effects of remimazolam on cognition and brain activity and connectivity at rest, during noxious stimulation, and during a memory encoding task

Eligibility

Min Age: 18 YearsMax Age: 59 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called Peripheral Nerve Stimulation and a drug called Remimazolam for people with anesthesia, pain, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 59 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGRemimazolam

Subjects in this group will receive an intravenous infusion of this drug, during a portion of the study.

DEVICEPeripheral Nerve Stimulation

Experimental acute pain stimulus will be delivered using a nerve stimulator. These painful shocks will be paired with a fixed number of the experimental cues, in a pattern that appears random to participants.