RecruitingNCT07292649

Maternal Expectations on Labor Analgesia and Risk of Postpartum Depression: An Observational Study


Sponsor

University of Padova

Enrollment

3,640 participants

Start Date

Jan 8, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

Postpartum Depression (PPD) is defined as the development of depression at any time during the first year after childbirth¹. Its prevalence ranges from 15% to 20%. It can manifest with symptoms such as depressed mood, loss of interest and energy, insomnia, anxiety, and may even lead to suicidal ideation. The consequences are numerous, both physical and psychological, with long-term repercussions on the mother-infant bond, family dysfunction, and the development of emotional and cognitive disorders in children. The etiology of PPD is multifactorial, but numerous recent studies have focused on the role of labor pain and its management with labor analgesia techniques. The aim of the present study is therefore to assess whether there is a difference in the incidence of PPD between parturients whose expectations regarding labor analgesia were met ('expectations met' group) versus those whose expectations were unmet.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria4

  • Signed informed consent
  • Planned vaginal delivery (spontaneous or induced)
  • Pregnancy
  • Age > 18 years

Exclusion Criteria5

  • Allergy to local anesthetics
  • Language barrier
  • Contraindications to labor analgesia
  • Delivery by Cesarean section
  • Known history of psychiatric disorders (including major depression)

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Interventions

PROCEDUREEpidural analgesia

Analgesia via epidural catheter using local anesthetic ± opioid, administered on patient request during labor.

PROCEDURESpinal analgesia for labour pain

Single-shot spinal analgesia

OTHERNo neuraxial analgesia

Patients did not received spinal or epidural labour analgesia


Locations(1)

University Hospital of Padova

Padova, Veneto, Italy

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NCT07292649


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