Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis

This study tests whether focused ultrasound applied to the spleen — a non-invasive technique that stimulates immune-regulating nerve pathways — can reduce inflammation and improve symptoms in people with active rheumatoid arthritis who are already on disease-modifying drugs. **You may be eligible if...** - You are 18 or older - You have been diagnosed with rheumatoid arthritis by standard criteria - You have a positive test for rheumatoid factor (RF) or anti-CCP antibodies - Your disease is at least moderately active (DAS28-CRP score above 3.8, with 4 or more tender and 4 or more swollen joints) - Your inflammation marker (CRP) is elevated (10 mg/L or higher) - You are on a stable dose of disease-modifying medication **You may NOT be eligible if...** - You are unable to provide consent - You have a condition preventing at-home device use or scheduled clinic visits Talk to your doctor to see if this trial is right for you.