The Effect of Virtual Reality Therapy on Upper Extremity Functions in Subacute Stroke Patients Receiving Rehabilitation
The Effect of Virtual Reality Therapy on Upper Extremity Functions in Subacute Stroke Patients Receiving Conventional Rehabilitation and Action Observation Therapy: A Randomized Controlled Single-Blind Study
Istanbul Physical Medicine Rehabilitation Training and Research Hospital
38 participants
Aug 15, 2025
INTERVENTIONAL
Conditions
Summary
Stroke ranks second among the leading causes of death worldwide and third among the causes of disability. In stroke patients, motor impairment typically affects facial movements and the upper and lower extremities unilaterally. Upper extremity involvement, in particular, negatively impacts patients' activities of daily living, such as eating and dressing. Various rehabilitation methods are used to improve the function of the paretic upper extremity in stroke patients. Action Observation Therapy and Virtual Reality are among the rehabilitation approaches currently used to support upper extremity rehabilitation. In our study, patients will be randomly divided into two groups: one group will receive conventional rehabilitation and Action Observation Therapy, while the other group will additionally receive Virtual Reality therapy. This study aims to investigate the contribution of Virtual Reality therapy, when added to conventional rehabilitation and Action Observation Therapy, to the recovery of the paretic upper extremity in patients with subacute stroke.
Eligibility
Inclusion Criteria6
- Patients over the age of 18
- Patients in the subacute phase of stroke (between 6 weeks and 6 months post-stroke)
- Patients with a first-ever stroke
- Brunnstrom stage 3 or above for both upper extremity and hand
- Mini-Mental State Examination (MMSE) score \>=20
- No major medical condition that would prevent participation in the treatment
Exclusion Criteria7
- Presence of pain in the paretic shoulder severe enough to prevent exercise
- History of bilateral stroke
- Patients with global aphasia and/or cognitive impairment that significantly affects treatment compliance
- Patients with severe visual impairment
- Presence of unilateral spatial neglect
- Inability to maintain sitting balance
- Modified Ashworth Scale \> 4 in the hemiplegic arm
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Camera controlled virtual reality games for upper extremity
Personalized conventional exercises for hemiparesis after stroke
Rehabilitation method that involves patients watching video recordings of purposeful upper extremity movements designed for daily life activities followed by physically attempting the same movements.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07299162