RecruitingNot ApplicableNCT07301528

Comparison of ESP and QL Blocks for Postoperative Pain in Pediatric Appendectomy (ESP-QLB)

Comparative Effects of Erector Spinae Plane and Quadratus Lumborum Blocks on Postoperative Pain and Analgesic Requirement in Pediatric Appendectomy: A Prospective Randomized Controlled Trial


Sponsor

Zeycan Kahya

Enrollment

60 participants

Start Date

Dec 12, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective randomized controlled clinical trial aims to compare the analgesic effectiveness of the Erector Spinae Plane (ESP) block and the Quadratus Lumborum (QL) block in pediatric patients undergoing appendectomy. Both regional anesthesia techniques have been shown to reduce opioid requirements and improve postoperative recovery in children; however, there is limited evidence directly comparing their efficacy. In this study, eligible participants will be randomly assigned to receive either an ESP or a QL block in addition to standard general anesthesia before surgical incision. Postoperative outcomes will include pain scores, total opioid consumption, time to first analgesic requirement, mobilization time, parental satisfaction, length of hospital stay, block-related complications and block performance time. The findings are expected to guide clinicians in selecting the most effective regional anesthesia technique for postoperative pain control in pediatric appendectomy.


Eligibility

Min Age: 3 YearsMax Age: 13 Years

Inclusion Criteria5

  • Patients aged 3-13 years
  • Diagnosis of acute appendicitis requiring appendectomy
  • ASA physical status I-II
  • Planned general anesthesia with intraoperative regional block (ESP or QL block)
  • Written informed consent obtained from parents or legal guardians

Exclusion Criteria8

  • Refusal of regional block by family or anesthesia team
  • Coagulopathy or anticoagulant medication use
  • Local infection at the block injection site
  • Known allergy or contraindication to local anesthetics
  • Neurological or neuromuscular disorders
  • Cognitive impairment preventing postoperative pain assessment
  • Conversion to open surgery
  • Intraoperative complications requiring deviation from study protocol

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Interventions

DRUGQuadratus Lumborum Block (QLB)

Ultrasound-guided transmuscular QL block performed under general anesthesia using 0.25% bupivacaine (0.5 mL/kg) before surgical incision.

DRUGErector Spinae Plane Block

Ultrasound-guided ESP block at the L1 level under general anesthesia using 0.25% bupivacaine (0.5 mL/kg) before surgical incision.


Locations(2)

Kutahya City Hospital Anesthesia and Reanimation Department

Kütahya, Kütahya, Turkey (Türkiye)

Kutahya City Hospital

Kütahya, Turkey (Türkiye)

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NCT07301528


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