RecruitingPhase 3NCT06386770

Systemic Versus Local Dexmedetomidine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block

Systemic Versus Local Dexamedetomedine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block in Kidney Exploration Surgeries ,A Randomized Controlled Trial


Sponsor

Aswan University

Enrollment

75 participants

Start Date

Jun 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this study is to investigate the analgesic effect of local versus systemic dexamedetomedine as adjuvant to bupivacaine in erector spinae block in kidney exploration surgeries.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria3

  • •. kidney exploration surgeries.
  • ASA I/II patients.
  • BMI \<35

Exclusion Criteria5

  • Getting opioid analgesics prior to surgery.
  • Local infections at the site where needle for block is to be inserted.
  • ASAIII/IV.
  • Pregnancy.
  • History of drug addiction or alcohol abuse or a psychiatric illness,

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Interventions

DRUGDexmedetomidine Injection [Precedex]

Group ΙI (group DL): erector spinae block will receive 30 ml (28 ml bupivacaine 0.25% plus dexamedetomedine (0.5µg/kg) diluted in 2ml normal saline Na cl 0,9% ) + 10ml IV normal saline will be injected over 10 min after 10 min from the induction of general anesthesia

DRUGBupivacaine Hydrochloride

.Group Ι Block only (group BO) (control group): erector spinae block will receive 30 ml ( 28 ml bupivacaine 0.25% +2ml normal saline Na cl 0,9 %) +10ml IV normal saline will be injected over 10 min after 10 min from the induction of general anesthesia

DRUGDexmedetomidine in 0.9 % NaCl 200 Mcg/50 mL (4 Mcg/mL) INTRAVEN INFUSION BOTTLE (ML)

Group III (group D IV): erector spinea block will receive 30 ml ( 28 ml bupivacaine 0.25% +2ml normal saline Na cl 0,9%) + dexamedetomedine (0.5µg/kg) diluted with 10 ml normal saline IV infusion by syringe pump over 10 min after 10 min from the induction of general anesthesia.


Locations(1)

Aswan University

Aswān, Aswan Governorate, Egypt

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NCT06386770


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