Preventing Muscle Loss After Bariatric Surgery: Protein-Collagen Supplementation and Resistance Exercise
Preventing Muscle Loss in the Early Postoperative Period of Bariatric Surgery With a Combination of Whey Protein, Hydrolyzed Collagen, and Resistance Exercise: A Prospective, Randomized, Controlled Clinical Study
Medipol University
35 participants
Aug 2, 2022
INTERVENTIONAL
Conditions
Summary
The aim of this clinical trial is to investigate the effectiveness of collagen, considered a new approach to prevent muscle mass loss after bariatric surgery, and to demonstrate the relationship between this effect and exercise. The key questions it aims to answer are: Does whey protein supplementation with collagen combined with resistance exercise prevent muscle mass loss after bariatric surgery? Do whey protein supplementation with collagen combined with resistance exercise affect fat mass after bariatric surgery? Researchers will compare collagen with whey protein. The study groups and interventions to be implemented are summarized below: Group 1: Control Group (CG; n: 10) Whey protein supplementation will be administered Vitamin and mineral supplementation will be administered No resistance exercise will be performed The participants will eat according to bariatric surgery nutrition guidelines and perform physical activities. Group 2: Whey Protein + Collagen + Exercise Group (WPCEG; n: 10) Whey protein supplements with collagen will be given. Vitamin and mineral supplements will be given. Resistance exercise will be performed. They will eat according to bariatric surgery nutrition guidelines and perform physical activities. They will begin a resistance exercise program 4 weeks after surgery. Group 3: Whey Protein + Collagen + No Exercise Group (WPCG; n: 10) Whey protein supplements with collagen will be given. Vitamin and mineral supplements will be given. No resistance exercise will be performed. They will eat according to bariatric surgery nutrition guidelines and perform physical activities. Group 4: Whey Protein + Exercise Group (WPEG; n: 10) Whey protein supplements will be given. Vitamin and mineral supplements will be given. Resistance exercise will be performed. They will eat according to bariatric surgery nutrition guidelines and perform physical activities. A resistance exercise program will begin at 4 weeks post-operatively.
Eligibility
Inclusion Criteria6
- Being between 20-50 years old
- Body mass index; 35 ≤ BMI< 60 kg/m2
- Not being pregnant
- Not being addicted to alcohol and drugs
- Not having entered menopause
- No exercise restrictions
Exclusion Criteria8
- Having at least one of the following inflammatory bowel diseases, upper gastrointestinal bleeding, advanced psychiatric diseases, cancer, and kidney failure.
- using statins
- be pregnant
- Being addicted to alcohol and drugs
- to have entered menopause
- Having exercise restrictions
- Becoming a professional athlete
- Having done more than 60 minutes of regular and structured exercise per week in the last year
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Interventions
Oral whey protein supplement provided daily according to bariatric surgery nutrition protocol.
Oral hydrolyzed collagen supplement provided daily in combination with whey protein.
Routine vitamin and mineral supplementation according to bariatric surgery follow-up protocol.
Structured resistance exercise program initiated at postoperative week 4, supervised, 3 times per week.
Locations(1)
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NCT07303543