RecruitingNot ApplicableNCT07304479

Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery

Effects of Sevoflurane Versus Desflurane Anesthesia Under Protective Mechanical Ventilation for Robotic Assisted Surgery on Airway Plateau Pressure: a Randomized, Prospective, Blinded Pilot Study


Sponsor

National and Kapodistrian University of Athens

Enrollment

50 participants

Start Date

May 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Inhalational anesthetics, when used in abdominal surgery, offer advantages of lung protection and reduced alveolar inflammation. There is little literature, however, in the comparative use of sevoflurane versus desflurane anesthesia in patients undergoing abdominal robotic-assisted surgery and their effects on lung mechanics.


Eligibility

Min Age: 18 YearsMax Age: 87 Years

Inclusion Criteria3

  • Age 18 to 87 years
  • Undergoing elective robotic-assisted abdominal surgery
  • ASA physical status I-III

Exclusion Criteria6

  • ASA IV or V
  • Emergency surgery
  • Renal insufficiency
  • Clinically significant respiratory disease
  • Cardiomyopathy
  • Uncontrolled hypertension

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Interventions

DRUGSevoflurane (Volatile Anesthetic)

Sevoflurane for robotic assisted laparoscopic surgery

DRUGDesflurane (volatile anesthetic)

Desflurane for robotic assisted laparoscopic surgery


Locations(1)

Aretaieion University Hospital

Athens, Greece

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NCT07304479


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