RecruitingNCT07308795

The Ultrasonographic Evaluation of Abdominal Accessory Respiratory Muscle Thickness in Patients With Parkinson's Disease: Correlation With Disease Severity and Expiratory Respiratory Muscle Strength


Sponsor

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Enrollment

36 participants

Start Date

Dec 29, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Parkinson's disease is a neurodegenerative disorder characterized by both motor and non-motor symptoms. The involvement of respiratory muscles can lead to impairments in respiratory function in these patients. In this study is to evaluate the thickness of abdominal accessory respiratory muscles using ultrasonography in patients with Parkinson's disease. Additionally, the relationship between disease severity and expiratory respiratory muscle strength will be examined. The study will include Parkinson's patients at different stages of the disease, with respiratory muscle thickness measured via ultrasonography. The collected data will then be compared with disease severity and expiratory muscle strength.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study uses ultrasound imaging to measure the thickness of breathing muscles in the abdomen in people with Parkinson's disease, and examines how these muscle changes relate to disease severity and the strength of muscles used for breathing out. **You may be eligible if...** - You are over 18 years old - You have been diagnosed with Parkinson's disease at stages 1, 2, or 3 on the Modified Hoehn and Yahr scale (mild to moderate) - Your cognitive function is relatively preserved (MMSE score above 23) - Your BMI is under 30 **You may NOT be eligible if...** - You are an active smoker - You have an active chest disease - You have hemodynamic instability or unstable vital signs - Your Parkinson's disease is not well controlled with medication - You have Parkinson Plus syndrome (a related but different condition) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

İstanbul Fizik Tedavi Ve Rehabilitasyon Eğitim Ve Araştirma Hastanesi

Istanbul, BAHÇELİEVLER, Turkey (Türkiye)

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NCT07308795


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