Parkinson Disease (PD) Clinical Trials

22 recruiting

Frequently Asked Questions

Common questions about Parkinson Disease (PD) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting
Not Applicable

Rehabilitation With Dual-task Exercises to Improve Balance in Patients With Parkinson's Disease

Parkinson Disease (PD), Postural Balance
G. d'Annunzio University74 enrolled1 locationNCT07013214
Recruiting
Not Applicable

Motor and Cognitive Exercise in Parkinson's Disease.

Parkinson Disease (PD)
Annemette Lokkegaard48 enrolled1 locationNCT07465107
Recruiting

Validation of α-synuclein Modifications in Parkinson's dIsoRder Evolution

Parkinson Disease (PD)
Casa di Cura IGEA1,200 enrolled4 locationsNCT06941012
Recruiting

Objective Mobility Assessment Using Wearable Technology for Clinical Application in Parkinson's Disease: From Validation to Fall Prediction

Parkinson Disease (PD)
Northumbria University60 enrolled1 locationNCT07281755
Recruiting

Clinical Validity of the DANU Sports System for Gait and Balance Assessment in Parkinson's Disease

Parkinson Disease (PD)Healthy (Controls)
Northumbria University60 enrolled2 locationsNCT07281794
Recruiting
Not Applicable

Effects of Transcranial Direct Current Stimulation Combined With Nordic Walking on Gait and Balance in Parkinson's Disease

Gait DisordersParkinson Disease (PD)Postural Balance
Universidade Metodista de Piracicaba40 enrolled1 locationNCT07381907
Recruiting
Phase 2

D-SPARK: A Clinical Trial of D-Serine for Modifying Parkinson's Disease Progression

Parkinson's DiseaseParkinson Disease (PD)
Haukeland University Hospital100 enrolled11 locationsNCT07312110
Recruiting

The Ultrasonographic Evaluation of Abdominal Accessory Respiratory Muscle Thickness in Patients With Parkinson's Disease: Correlation With Disease Severity and Expiratory Respiratory Muscle Strength

Parkinson Disease (PD)Maximum Inspiratory PressureMaximum Expiratory Pressure+1 more
Istanbul Physical Medicine Rehabilitation Training and Research Hospital36 enrolled1 locationNCT07308795
Recruiting
Phase 1Phase 2

Clinical Study to Evaluate XS411 in Treatment of Early-onset Parkinson's Disease

Parkinson Disease (PD)
XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.90 enrolled1 locationNCT07166757
Recruiting
Not Applicable

Safety and Usability of the Cionic Neural Sleeve for Parkinson's Disease

Parkinson Disease (PD)
Cionic, Inc.10 enrolled2 locationsNCT07284823
Recruiting
Not Applicable

Early Stage of Alzheimer's and Parkinson's Diseases, HearIng Relevance (SAPHIR)

Healthy ParticipantsMild Cognitive Impairment (MCI) AmnesticParkinson Disease (PD)
Cilcare SAS309 enrolled4 locationsNCT07083089
Recruiting
Not Applicable

Virtual Reality on Balance of Parkinson's Disease

Physical TherapyParkinson Disease (PD)Immersive Virtual Reality
Instituto de Investigación Sanitaria Aragón50 enrolled1 locationNCT07274514
Recruiting
Not Applicable

Empathy and (Self-)Compassion in Parkinson's Disease Patients and Caregivers

Parkinson Disease (PD)
Alain Kaelin30 enrolled1 locationNCT07097298
Recruiting
Not Applicable

Daily Amino Acid Supplementation for People With Parkinson's Disease

Parkinson Disease (PD)
Cristina Colon-Semenza30 enrolled1 locationNCT07115563
Recruiting
Not Applicable

Modulate Tremor Severity With Low-intensity Focused Ultrasound Stimulation Targeting the Deep Nucleus of Patients With Refractory Hand Tremor.

Parkinson Disease (PD)Essential TremorDystonic Tremor+1 more
National Taiwan University Hospital12 enrolled1 locationNCT07172295
Recruiting

Which Tools Better Predict Fall Risk in Parkinson's Disease: A Comparative Study of Objective, Self-Reported, and Functional Balance Assessment

Parkinson DiseaseParkinsonPARKINSON DISEASE (Disorder)+2 more
Bezmialem Vakif University40 enrolled1 locationNCT07148700
Recruiting
Phase 1

Testing if PDR-001 Can Safely and Effectively Remove Harmful Brain Protein in Parkinson's Disease

Parkinson Disease (PD)
Ruijin Hospital12 enrolled1 locationNCT07157345
Recruiting
Not Applicable

Robotic Apparel to Prevent Freezing of Gait in Parkinson Disease

Parkinson Disease (PD)
Harvard Medical School (HMS and HSDM)20 enrolled2 locationsNCT06602544
Recruiting
Not Applicable

Steps Against the Burden of Parkinson's Disease

Parkinson Disease (PD)
The University of New South Wales42 enrolled1 locationNCT07057219
Recruiting

Efficacy and Safety of Entacapone Combined With Madopar in the Treatment of Early Parkinson's Disease: An Observational, Multicenter, Case-Control Study

Parkinson Disease (PD)
Yousheng Xiao216 enrolled1 locationNCT06928519