RecruitingNCT07309991

Postoperative Hypoxemia Increases the Risk of Anastomotic Leak After Radical Esophagectomy

Sponsor

Sun Yat-sen University

Enrollment

2,500 participants

Start Date

Jan 1, 2021

Study Type

OBSERVATIONAL

Conditions

Esophageal Carcinoma Esophageal Adenocarcinoma Esophagectomy PaO2 Esophageal Anastomotic Leakeage

Summary

This study aims to determine whether postoperative hypoxia (arterial partial pressure of oxygen (PaO₂)\<80 mmHg) is an independent risk factor for anastomotic leakage after esophagectomy. The investigators conducted a retrospective analysis of cases from their center over the past five years, stratifying patients into Low Pa0₂ Group and Normal Pa0₂ Group based on postoperative oxygen levels and comparing the incidence of anastomotic leakage between the groups. The goal is to establish whether hypoxia is a causative risk factor and whether correcting it can reduce the risk of anastomotic leakage.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a new treatment for people with esophageal adenocarcinoma, esophageal anastomotic leakeage, and other related conditions. The study is currently recruiting participants at 6 locations. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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