Esophagectomy Clinical Trials

9 recruiting

Esophagectomy Trials at a Glance

17 actively recruiting trials for esophagectomy are listed on ClinicalTrialsFinder across 6 cities in 11 countries. The largest study group is Not Applicable with 2 trials, with the heaviest enrollment activity in Brest, Basel, and Amsterdam. Lead sponsors running esophagectomy studies include Assistance Publique - Hôpitaux de Paris, Cabrini Clinical Education and Research Institute, and Alfred Health.

Browse esophagectomy trials by phase

Treatments under study

About Esophagectomy Clinical Trials

Looking for clinical trials for Esophagectomy? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Esophagectomy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Esophagectomy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting

Outcomes After Esophagectomy With a Focus on Minimally Invasive Esophagectomy and Quality of Life

Esophageal CancerEsophagectomy
University of Pittsburgh3,500 enrolled2 locationsNCT00260559
Recruiting
Not Applicable

Balloon Dilation in Patients Undergoing Minimally Invasive Ivor Lewis Esophagectomy and Its Effect on Reducing DGCE

Delayed Gastric Conduit Emtpying (DGCE)Minimally-invasive Esophagectomy
University Hospital, Basel, Switzerland116 enrolled1 locationNCT07355374
Recruiting

Mayo Clinic Upper Digestive Disease Survey

Esophageal CancerEsophagus CancerEsophageal Neoplasms+6 more
Mayo Clinic1,000 enrolled1 locationNCT02530983
Recruiting
Phase 2Phase 3

Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

EsophagectomyEsophageal Cancer SurgeryDelayed Gastric Emptying Following Procedure+4 more
The Cleveland Clinic170 enrolled1 locationNCT06721520
Recruiting

Shanghai Clinical Cohort - Esophageal Cancer

Esophageal CancerEsophagectomy
Shanghai Chest Hospital2,116 enrolled1 locationNCT07312526
Recruiting

Infectious Complications After Esophagectomy

PneumoniaPostoperative ComplicationsEsophagectomy+1 more
Assistance Publique - Hôpitaux de Paris350 enrolled2 locationsNCT06911658
Recruiting
Phase 4

Stellate Ganglion Block

LobectomyEsophagectomyPneumonectomy
University of Minnesota48 enrolled1 locationNCT06271707
Recruiting

Oesophagectomy and Chest Wall and Respiratory Function

Esophageal CancerEsophagectomyRespiratory Function Loss
Imperial College London100 enrolled1 locationNCT03835273
Recruiting

Perioperative Dynamics of Energy Expenditure in Oesophagectomy Patients

Oesophagectomy
University Hospital, Rouen120 enrolled4 locationsNCT06921668
Recruiting
Not Applicable

Evolution of the Lymphocyte Phenotype in Patients with Infection in Intensive Care Unit

Patients Undergoing EsophagectomyPatients with Severe PolytraumaPatients with Severe Neurological Lesion+1 more
University Hospital, Brest80 enrolled1 locationNCT06415474
Recruiting

Investigating Outcomes of Elective Robotic Transhiatal Esophagectomy

Esophagectomy
Northwestern University25 enrolled1 locationNCT05950438
Recruiting

Metachronic Brain Metastases After Esophagectomy for Esophageal Cancer (METABREC)

Esophageal NeoplasmsBrain MetastasesEsophagectomy
Universitaire Ziekenhuizen KU Leuven10,000 enrolled8 locationsNCT04654975
Recruiting

Delineating gastric emptying after major gastro-oesophageal surgery using real time MRI

OesophagectomyGastric conduit dysmotilityGastric Conduit Emptying Failure
Alfred Health36 enrolled1 locationACTRN12623000966695
Recruiting

Endoscopic and histologic characterization of esophagogastric neojunction after esophagectomy

Prevalence of new cardiac epithelium after esophagectomyEsophagogastric neojunction characterization after esophagectomy
Instituto Portugues de Oncologia de Lisboa Francisco Gentil20 enrolled1 locationACTRN12616001247460
Recruiting

Comparison of pre- and peri operative immunonutrition to standard formula in patients undergoing surgical resection of oesophageal cancer

Patients undergoing oesophagectomy for cancer resection
Professor Glyn Jamieson232 enrolled1 locationACTRN12611000178943
Recruiting

An Antireflux Anastomosis Following Oesophagectomy

Post Oesophagectomy Reflux
University of Melbourne, Department of Surgery, Austin Hospital80 enrolled1 locationACTRN12605000587606
Recruiting
Phase 2

Does the use of nizatidine (Tazac) as a prokinetic agent improve gastric emptying in patients who have had an oesophagectomy for oesophageal cancer?

Delayed gastric emptying post oesophagectomy for oesophageal cancer
Cabrini Clinical Education and Research Institute20 enrolled1 locationACTRN12605000454673