RecruitingPhase 4NCT07313371
Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder
Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder: a Randomized Clinical Trial.
Sponsor
University of Sao Paulo General Hospital
Enrollment
36 participants
Start Date
Jan 28, 2026
Study Type
INTERVENTIONAL
Conditions
Summary
This is a single-center, randomized intervention study in a volunteer population of patients with cocaine/crack use disorder to evaluate the pharmacological treatment of cocaine/crack craving, comparing the drug clonidine with the active placebo clonazepam.
Eligibility
Min Age: 18 YearsMax Age: 65 Years
Inclusion Criteria4
- Patients hospitalized in the adult Alcohol and Drugs ward of the Perdizes Institute (IPer) at the Hospital das Clínicas, University of São Paulo Medical School
- DSM-5 criteria for cocaine and/or crack use disorder
- Voluntarily seeking treatment
- Must be able to swallow pills
Exclusion Criteria4
- Inability to read and/or understand the study questionnaires
- benzodiazepine use disorder
- opioid use disorder
- alcohol use disorder
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Interventions
DRUGclonidine
Clonidine 0,1 mg bid
DRUGclonazepam 0,25 mg
clonazepam 0,25 mg bid
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07313371
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