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RecruitingPhase 4NCT07313371

Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder

Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder: a Randomized Clinical Trial.

Sponsor

University of Sao Paulo General Hospital

Enrollment

36 participants

Start Date

Jan 28, 2026

Study Type

INTERVENTIONAL

Conditions

Cocaine Use DisorderCrack Abuse or Dependence

Summary

This is a single-center, randomized intervention study in a volunteer population of patients with cocaine/crack use disorder to evaluate the pharmacological treatment of cocaine/crack craving, comparing the drug clonidine with the active placebo clonazepam.

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called clonazepam 0,25 mg and a drug called clonidine for people with cocaine use disorder and crack abuse or dependence. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGclonidine

Clonidine 0,1 mg bid

DRUGclonazepam 0,25 mg

clonazepam 0,25 mg bid

Locations(1)

Instituto Perdizes

São Paulo, São Paulo, Brazil

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NCT07313371

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