RecruitingNot ApplicableNCT04927143

Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives


Sponsor

Wake Forest University Health Sciences

Enrollment

600 participants

Start Date

Sep 15, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Combatting the rise of the opioid epidemic is a central challenge of U.S. health care policy. A promising approach for improving welfare and decreasing medical costs of people with substance abuse disorders is offering incentive payments for healthy behaviors. This approach, broadly known as "contingency management" in the medical literature, has repeatedly shown to be effective in treating substance abuse. However, the use of incentives by treatment facilities remains extremely low. Furthermore, it is not well understood how to design optimal incentives to treat opioid abuse. This project will conduct a randomized evaluation of two types of dynamically adjusting incentive schedules for people with opioid use disorders or cocaine use disorders: "escalating" schedules where incentive amounts increase with success to increase incentive power, and "de-escalating" schedules where incentive amounts decrease with success to improve incentive targeting. Both schemes are implemented with a novel "turnkey" mobile application, making them uniquely low-cost, low-hassle, and scalable. Effects will be measured on abstinence outcomes, including longest duration of abstinence and the percentage of negative drug tests. In combination with survey data, variation from the experiment will shed light on the barriers to abstinence more broadly and inform the understanding of optimal incentive design.


Eligibility

Min Age: 18 Years

Inclusion Criteria9

  • Age at least 18 years old;
  • Meet DSM-5 OUD, CoUD, or MUD criteria as evidenced by an OUD CPT code F11\* (opioid related disorders), a CoUD CPT code F14\* (cocaine related disorders), a MUD CPT code F15.1/F15.2 or other clinical notes indicating illicit opioid/cocaine/methamphetamine use for treatment
  • Have access to a smartphone (iOS or Android) with data plan and willing to download DynamiCare app;
  • Have an email and can access it from their smartphone;
  • Are in residential, day (PHP), partial day (IOP), or outpatient (OP) AODA treatment;
  • Are likely to be helped by contingency management because at least ONE of the following conditions is true:
  • Were first enrolled in residential, PHP, or IOP substance use treatment no longer than 2 treatment weeks (14 days/encounters of treatment) prior to providing informed consent.
  • Used non-medical opioids, cocaine, and/or methamphetamine within the last 21 days.
  • Understands English.

Exclusion Criteria2

  • Have evidence of active (non-substance related) psychosis that might impair participation as determined by the PI.
  • Has significant cognitive impairment that might confound participation as determined by the PI or are so significantly cognitively impaired that they have a legal guardian.

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Interventions

BEHAVIORALApp-Based Contingency Management

Participants will receive financial incentives for submitting randomly generated drug-negative saliva tests across the intervention period.

BEHAVIORALSham Control

Participants get access to the DynamiCare app but will not be provided with financial incentives.


Locations(2)

Rogers Behavioral Health

Oconomowoc, Wisconsin, United States

Advocate Aurora Behavioral Health Services

Wauwatosa, Wisconsin, United States

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NCT04927143


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