RecruitingNCT07313462

Escalation vs. Induction Therapy Strategy in Patients With Early-Onset MS After Age 50


Sponsor

University Hospital, Strasbourg, France

Enrollment

830 participants

Start Date

Feb 7, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The objective of this study is to evaluate the risk of inflammatory disease activity by retrospectively comparing two therapeutic strategies (escalation group and induction group). The investigators also aim to identify factors associated with inflammatory relapse and treatment-related complications.


Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This registry study compares two treatment strategies in people who developed relapsing-remitting multiple sclerosis (MS) after age 50: starting with a moderate-strength MS drug and escalating if needed, versus starting immediately with a high-strength drug. It aims to find the better approach for older adults newly diagnosed with MS. **You may be eligible if...** - Your first MS symptoms appeared after age 50 - You started MS treatment within 2 years of your first symptoms - You are currently on or have been treated with either moderate-strength MS drugs (such as teriflunomide, dimethyl fumarate, glatiramer acetate, interferon beta) or high-potency drugs (such as natalizumab, ocrelizumab, cladribine, fingolimod) **You may NOT be eligible if...** - You have primary or secondary progressive MS (not relapsing-remitting) - Your first MS episode occurred before age 50 Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Centre d'Investigation Clinique - CHU de Strasbourg - France

Strasbourg, France

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NCT07313462


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