RecruitingPhase 2NCT07317206

Ayahuasca, Esketamine and PTSD

Effects of Single Dose of Ayahuasca or Esketamine on Posttraumatic Stress Disorder: a Randomized, Double-blinded Study


Sponsor

University of Sao Paulo

Enrollment

10 participants

Start Date

Dec 20, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Double-blind, randomized trial comparing a single dose of oral ayahuasca or esketamine in patients with posttraumatic stress disorder.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria1

  • posttraumatic stress disorder

Exclusion Criteria1

  • psychiatric and other medical comorbidities

Interventions

DRUGAyahuasca

oral ayahuasca

DRUGEsketamine

oral esketamine


Locations(1)

Hospital das Clínicas da FMRP-USP

Ribeirão Preto, São Paulo, Brazil

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NCT07317206


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