The Use of Rhythmic Light Therapy in Mild Cognitive Impairment
Icahn School of Medicine at Mount Sinai
20 participants
Dec 8, 2025
INTERVENTIONAL
Conditions
Summary
In this within-subjects, crossover study, participants will undergo Electroencephalogram (EEG) recordings before, during, and after each of three 1-hour sessions. All participants will experience all three conditions: (1) dual-frequency visual (10 and 40 Hz), (2) single-frequency visual (40 Hz), and (3) non-rhythmic stimulation. EEG spectral power and amplitude coupling will be analyzed to determine whether stimulation-induced increases in alpha-gamma neural synchrony translate to improvements in cognitive performance.
Eligibility
Inclusion Criteria1
- History of Mild Cognitive Impairment with a Montreal Cognitive Assessment score between 18 and 25
Exclusion Criteria4
- History of epilepsy or photosensitivity
- Blindness or other obstructive vision conditions
- retinal diseases
- presence of another brain disease accounting for their cognitive status
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Interventions
Red Flickering Light programed to three different visual stimulations
Locations(1)
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NCT07318038