RecruitingNot ApplicableNCT07322965

Evaluation of BRUDYGLAUCO (DHA + Citicoline) in Patients With Glaucoma

Evaluation of the Effect of BRUDYGLAUCO (DHA + Citicoline) in Patients With Glaucoma


Sponsor

Institut Catala de Retina

Enrollment

108 participants

Start Date

Apr 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to evaluate the effects of BrudyGlauco, a nutritional supplement containing DHA (docosahexaenoic acid) and citicoline, on visual function in people with glaucoma. Glaucoma is a progressive optic neuropathy that can lead to vision loss. Current treatments focus on lowering eye pressure, but there are other pathogenic factors and the use of additional therapies that could protect or regenerate the optic nerve would be beneficial. This is a randomized, double-blind, placebo-controlled, and multicenter clinical trial. Participants will be randomly assigned to receive either BrudyGlauco or a placebo for 12 months. The study will assess changes in visual field, safety, and treatment adherence. The trial is being conducted at the Institut Català de Retina (ICR) and Hospital de la Esperanza. Participants will undergo regular eye exams, visual field tests, and follow-ups to monitor potential improvements in visual function. The results of this study will help determine if BrudyGlauco can provide neuroprotective benefits for people with glaucoma and improve their quality of life.


Eligibility

Min Age: 50 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a nutritional supplement called BRUDYGLAUCO — which contains DHA (an omega-3 fatty acid) and citicoline — to see if it can slow the loss of vision in people with glaucoma. Glaucoma is a disease where the optic nerve gradually gets damaged, leading to vision loss. **You may be eligible if...** - You are 50–75 years old - You have been diagnosed with chronic glaucoma (any type) in at least one eye - Your glaucoma has caused measurable damage to the optic nerve and your visual field, confirmed by imaging - You have had at least 4 reliable visual field tests before the study **You may NOT be eligible if...** - You have taken any vitamins or nutritional supplements in the past month - You have neurological diseases, severe retinal diseases, or advanced cataracts that could affect vision testing - You take a medication called Lyrica (pregabalin), which affects visual fields - You have had eye surgery or laser treatment in the last 3 months, or have it planned - You are allergic to aspirin (there is a cross-reaction risk with citicoline) - Your visual field loss is either very mild or very severe (outside the study range) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTBrudyGlauco

Participants in the experimental group will receive BrudyGlauco, a dietary supplement containing docosahexaenoic acid (DHA) and citicoline.

DIETARY_SUPPLEMENTPlacebo

Participants in the placebo comparator group will receive identical-looking capsules containing sunflower oil.


Locations(2)

Institut Català de Retina

Barcelona, Barcelona, Spain

Hospital del Mar | Centre Esperança

Barcelona, Barcelona, Spain

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NCT07322965


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