Effectiveness of Low -Versus High -Volume High -Intensity Interval Training in Patients With Chronic Heart Failure
Cairo University
45 participants
Dec 10, 2025
INTERVENTIONAL
Conditions
Summary
this study aims to investigate the effect of low vs high volume- high intensity interval training on functional capacity and quality of life in chronic heart failure patients
Eligibility
Inclusion Criteria4
- Chronic stable heart failure patient with reduced ejection fraction (EF \<40)
- Age Above 18 years old
- Both males and females
- The ability to provide informed consent
Exclusion Criteria18
- Based on the Scientific Statement from the American Heart Association: contraindications for exercise Testing and Training. (Fletcher et al., 2013)
- Acute myocardial infarction (MI), within 2 days
- Ongoing unstable angina
- Uncontrolled cardiac tachy or brady arrhythmia with hemodynamic compromise
- Active endocarditis
- Symptomatic severe aortic stenosis
- Decompensated heart failure
- Acute pulmonary embolism, pulmonary infarction, or deep vein thrombosis
- Acute myocarditis or pericarditis
- Acute aortic dissection
- Physical disability that precludes safe and adequate testing or training
- Known obstructive left main coronary artery stenosis
- Hypertrophic obstructive cardiomyopathy with severe resting gradient
- Recent stroke or transient ischemic attack
- Mental impairment with limited ability to cooperate
- Resting hypertension with systolic or diastolic blood pressures \>200/110 mmHg
- Uncorrected medical conditions, such as significant anemia, important electrolyte imbalance, and hyperthyroidism
- Acute decompensated heart failure NYHA class IV
Interventions
Low-volume HIIT (LV-HIIT) is a particularly time-efficient subtype of interval training, which has gained increasing attention in recent years. As per the previous definition, these brief training protocols typically involve≤10 min of intense exercise within a session lasting≤30 min including warm-up, recovery phases between intervals, and cool-down
long (2-4 min) bouts of high (not maximum) intensity exercise interspersed with recovery periods which have wide varieties in the protocols according to the intensity, duration, and number of intervals performed
standard medical treatment for chronic heart failure as per international guidlines
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07325942