RecruitingNCT07328178
Analysis of the Role of IgE Proteoforms in Health and Disease
Sponsor
KU Leuven
Enrollment
200 participants
Start Date
Jan 1, 2025
Study Type
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to evaluate the role of IgE proteoforms in healthy volunteers and in patients with type I allergy, patients with chronic spontaneous urticaria, patients with a recent history of anaphylaxis, patients with mastocytosis, patients with hereditary alpha tryptasemia, patients with X-linked agammaglobulinemia (XLA), and patients undergoing desensitization for venom or medication allergy.
Eligibility
Min Age: 18 Years
Inclusion Criteria2
- CSU and type I allergic diseases (including anaphylaxis and desensitization), atopic dermatitis, mastocytosis, XLA and HaT (informed consent, age: any available adult subject, gender: any available subject, clinical phenotype and specific information about the allergy (e.g. severity, medication, medical history, laboratory testing)
- Healthy controls (informed consent, age matched to the allergic patients, gender matched to the allergic patients, patient-reported symptoms related to allergy to aeroallergens, food, drugs, hymenoptera venom, CSU)
Exclusion Criteria2
- Absence of informed consent
- Age \< 18 years old
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Interventions
OTHERBlood sample collection
Blood sample collection
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07328178
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