Superselective Adrenal Arterial Embolization Versus Oral Spironolactone for Treatment of Idiopathic Hyperaldosteronism

This study compares two treatments for idiopathic hyperaldosteronism — a condition where both adrenal glands (small glands above your kidneys) produce too much of a hormone that raises blood pressure. The two approaches being compared are a minimally invasive procedure (targeted artery embolization to reduce hormone production) versus the standard medication spironolactone. **You may be eligible if...** - You are between 15 and 60 years old - You have been diagnosed with primary aldosteronism (excess aldosterone hormone causing high blood pressure) according to established guidelines - Testing has confirmed you have idiopathic hyperaldosteronism (both adrenal glands are overactive, not just one) **You may NOT be eligible if...** - Only one of your adrenal glands is overactive (unilateral hyperplasia) - Your kidney function is significantly reduced - You have had a stroke, heart stent, or heart attack in the past 3 months - You have a severe allergy to contrast dye used in imaging - You are pregnant or planning to become pregnant - You have another serious condition that prevents the embolization procedure - You have another form of secondary high blood pressure Talk to your doctor to see if this trial is right for you.