RecruitingNCT02832388

Primary Aldosteronism in Western Norway

Primary Aldosteronism: a Study of Diagnostic Approach and Treatment Outcome in Western Norway


Sponsor

Haukeland University Hospital

Enrollment

300 participants

Start Date

Jun 1, 2013

Study Type

OBSERVATIONAL

Conditions

Summary

In this study the investigators aim to identify and include consecutively patients with primary aldosteronism (PA) diagnosed in the Western and Mid-parts of Norway, to describe the characteristics of these patients, to explore the cardiac effects of PA before and after specific treatment, and to identify long-term outcomes after treatment. One subgroup of the PA patients perform echocardiography to assess left ventricular systolic myocardial function before and after treatment. One subgroup of PA patients perform cardiac MRI to assess myocardial mass, myocardial fibrosis and myocardial function in rest and during stress, before and after treatment. For the cardiac MRI substudy, the PA patients are compared with a group of healthy controls, also included in the study. From 2022 onwards, PA patients diagnosed or subtyped with adrenal vein sampling at Oslo University Hospital will additionally be included in the study, thereby providing a national registration of PA patients.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria2

  • Verified diagnosis or strong suspicion of primary aldosteronism
  • Age 18-85

Exclusion Criteria4

  • Active cancer disease at time of inclusion
  • Asthma/chronic obstructive pulmonary disease ,
  • Use of dipyridamole
  • Claustrophobia

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Locations(2)

Haukeland University Hospital

Bergen, Norway

Oslo University Hospital

Oslo, Norway

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NCT02832388


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